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Polycystin 1. Polycystin 1 ( PC1) is a protein that in humans is encoded by the PKD1 gene. [ 5][ 6] Mutations of PKD1 are associated with most cases of autosomal dominant polycystic kidney disease, a severe hereditary disorder of the kidneys characterised by the development of renal cysts and severe kidney dysfunction. [ 7]
SEMT Pielstick was a French company that designed and built large diesel engines. Its full name was Société d’Etudes des Machines Thermiques (Company of Thermal Machines Studies). Founded in 1948, SEMT was bought by MAN Diesel in 2006. During its existence as an independent company, SEMT manufactured engines for locomotives, naval vessels ...
Proprotein convertase 1, also known as prohormone convertase, prohormone convertase 3, or neuroendocrine convertase 1 and often abbreviated as PC1/3 is an enzyme that in humans is encoded by the PCSK1 gene. [5] PCSK1 and PCSK2 differentially cleave proopiomelanocortin and they act together to process proinsulin and proglucagon in pancreatic islets.
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. [ 1]
Proprotein convertase 2 ( PC2) also known as prohormone convertase 2 or neuroendocrine convertase 2 ( NEC2) is a serine protease and proprotein convertase PC2, like proprotein convertase 1 (PC1), is an enzyme responsible for the first step in the maturation of many neuroendocrine peptides from their precursors, such as the conversion of ...
PCI Express x16. PCI Express x1. PCI Express x16. Conventional PCI (32-bit, 5 V) PCI Express ( Peripheral Component Interconnect Express ), officially abbreviated as PCIe or PCI-e, [ 1] is a high-speed serial computer expansion bus standard, designed to replace the older PCI, PCI-X and AGP bus standards.
Opioids neuropeptide. Pro-opiomelanocortin ( POMC) is a precursor polypeptide with 241 amino acid residues. POMC is synthesized in corticotrophs of the anterior pituitary from the 267-amino-acid-long polypeptide precursor pre-pro-opiomelanocortin ( pre-POMC ), by the removal of a 26-amino-acid-long signal peptide sequence during translation. [ 5]
InterPro. Proinsulin is the prohormone precursor to insulin made in the beta cells of the Pancreatic Islets, specialized regions of the pancreas. In humans, proinsulin is encoded by the INS gene. [ 1][ 2] The pancreatic islets only secrete between 1% and 3% of proinsulin intact. [ 3] However, because proinsulin has a longer half life than ...