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Polycystin 1. Polycystin 1 ( PC1) is a protein that in humans is encoded by the PKD1 gene. [ 5][ 6] Mutations of PKD1 are associated with most cases of autosomal dominant polycystic kidney disease, a severe hereditary disorder of the kidneys characterised by the development of renal cysts and severe kidney dysfunction. [ 7]
The short-term effects of alcohol consumption range from a decrease in anxiety and motor skills and euphoria at lower doses to intoxication (drunkenness), to stupor, unconsciousness, anterograde amnesia (memory "blackouts"), and central nervous system depression at higher doses. Cell membranes are highly permeable to alcohol, so once it is in ...
Tupac Amaru Shakur ( / ˈtuːpɑːk ʃəˈkʊər / ⓘ TOO-pahk shə-KOOR; born Lesane Parish Crooks; June 16, 1971 – September 13, 1996), also known by his stage names 2Pac and Makaveli, was an American rapper and actor. Considered to be one of the greatest and most influential rappers of all time, [ 1][ 2][ 3] academics regard him as one of ...
Pilatus PC-12. The Pilatus PC-12 is a pressurized, single-engined, turboprop aircraft manufactured by Pilatus Aircraft of Stans, Switzerland since 1991. It was designed as a high-performance utility aircraft that incorporates a large aft cargo door in addition to the main passenger door. Due to its efficient, high-utility design, the PC-12 is ...
LOINC. 5639-0, 5640-8, 15120-9, 56478-1. Blood alcohol content ( BAC ), also called blood alcohol concentration or blood alcohol level, is a measurement of alcohol intoxication used for legal or medical purposes. [ 1] BAC is expressed as mass of alcohol per volume of blood.
Proprotein convertases (PPCs) are a family of proteins that activate other proteins. Many proteins are inactive when they are first synthesized, because they contain chains of amino acids that block their activity. Proprotein convertases remove those chains and activate the protein. The prototypical proprotein convertase is furin. [ 1]
Proprotein convertase 1, also known as prohormone convertase, prohormone convertase 3, or neuroendocrine convertase 1 and often abbreviated as PC1/3 is an enzyme that in humans is encoded by the PCSK1 gene. [5] PCSK1 and PCSK2 differentially cleave proopiomelanocortin and they act together to process proinsulin and proglucagon in pancreatic islets.
Oncology . Adenocarcinoma in situ(AIS) of the lung—previously included in the category of "bronchioloalveolar carcinoma" (BAC)—is a subtype of lung adenocarcinoma. It tends to arise in the distalbronchiolesor alveoliand is defined by a non-invasive growth pattern. This small solitary tumor exhibits pure alveolar distribution (lepidic growth ...