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Iron toxicity is classified as corrosive or cellular. Ingested iron can cause direct caustic injury to the gastrointestinal mucosa, resulting in nausea, vomiting, abdominal pain, and diarrhea. Significant fluid and blood loss can lead to hypovolemia.
The epidemiology, pharmacology, clinical manifestations, evaluation, and management of poisoning after acute iron ingestion and iatrogenic intravenous (IV) iron overdose are reviewed here. Iron deficiency, iron requirements, and iron balance are discussed separately.
In healthy adults, symptoms can begin by consuming as little as 20 mg/kg of elemental iron at one time. Very serious iron poisoning occurs at around 60 mg/kg and higher for children and adults ...
Iron overload, usually due to hemochromatosis, can be managed. To get rid of excess iron, you can have blood drawn or change your diet. Learn the symptoms, diagnosis, and treatment for this condition.
Hemochromatosis, or iron overload, is a condition in which your body stores too much iron. It’s often genetic. It can cause serious damage to your body, including to your heart, liver and pancreas.
Iron toxicity refers to the harmful effects of excess iron. It may occur when 1) people overdose on iron supplements, 2) take high-dose supplements for too long or 3) suffer from a chronic...
MECHANISM OF TOXICITY. Iron has local gastrointestinal effects followed by systemic effects (that do not occur without preceding GI toxicity following iron ingestion) Local effects: corrosive injury to the gastrointestinal mucosa resulting in vomiting, diarrhoea, haemetemesis, melaena and fluid losses that may result in hypovolaemia. Systemic ...
Poisonous Ingredient. Iron can be harmful in large amounts. Where Found. Iron is an ingredient in many mineral and vitamin supplements. Iron supplements are also sold by themselves. Types include: Ferrous sulfate (Feosol, Slow Fe) Ferrous gluconate (Fergon) Ferrous fumarate (Femiron, Feostat) Other products may also contain iron. Symptoms.
Iron poisoning typically occurs from ingestion of excess iron that results in acute toxicity. Mild symptoms which occur within hours include vomiting, diarrhea, abdominal pain, and drowsiness. [1] In more severe cases, symptoms can include tachypnea, low blood pressure, seizures, or coma. [2]
Hemochromatosis (he-moe-kroe-muh-TOE-sis) causes your body to absorb too much iron from the food you eat. Excess iron is stored in your organs, especially your liver, heart and pancreas. Too much iron can lead to life-threatening conditions, such as liver disease, heart problems and diabetes.