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About 25% of women who have hot flashes experience such significant symptoms that they seek medical care. About 1 in 3 women have more than 10 hot flashes a day.
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C++ [ 2] Google Search (also known simply as Google or Google.com) is a search engine operated by Google. It allows users to search for information on the Internet by entering keywords or phrases. Google Search uses algorithms to analyze and rank websites based on their relevance to the search query. It is the most popular search engine worldwide.
It was founded in 1971, and is currently the world's largest coffeehouse chain . As of November 2022, the company had 35,711 stores in 80 countries, 15,873 of which were located in the United States. Of Starbucks' U.S.-based stores, over 8,900 are company-operated, while the remainder are licensed.
Tadalafil is an annulated 2,5-diketopiperazine. [25] It is also a 1,2,3,4-tetrahydro-β-carboline. Tadalafil can be synthesized starting from (D)-tryptophan methyl ester and piperonal via a Pictet–Spengler reaction. This is followed by condensations with chloroacetyl chloride and methylamine to complete the diketopiperazine ring: [26]
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