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The interaction of VLA-5 with fibronectin plays an important role in regulating inflammatory cytokine production by human articular chondrocytes (From the Cell Migration Gateway ITGA5 ITGB1). α 5 β 1 -integrin is transported inside the cell by the kinesin KIF1C, [3] a kinesin-3 organelle transporter that walks along microtubules.
Integrin beta-6 is a protein that in humans is encoded by the ITGB6 gene. [5][6][7] It is the β6 subunit of the integrin αvβ6. Integrins are αβ heterodimeric glycoproteins which span the cell’s membrane, integrating the outside and inside of the cell. Integrins bind to specific extracellular proteins in the extracellular matrix or on ...
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