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Cardiomegaly (sometimes megacardia or megalocardia) is a medical condition in which the heart becomes enlarged. It is more commonly referred to simply as "having an enlarged heart ". It is usually the result of underlying conditions that make the heart work harder, such as obesity, heart valve disease, high blood pressure ( hypertension ), and ...
Atheroma. Atherosclerotic plaque from a carotid endarterectomy specimen. This shows the division of the common into the internal and external carotid arteries. An atheroma, or atheromatous plaque, is an abnormal accumulation of material in the inner layer of an arterial wall. [ 1][ 2] The material consists of mostly macrophage cells, [ 3][ 4 ...
Atherosclerosis[ a] is a pattern of the disease arteriosclerosis, [ 8] characterized by development of abnormalities called lesions in walls of arteries. This is a chronic inflammatory disease involving many different cell types, and driven by elevated levels of cholesterol in the blood. [ 9] These lesions may lead to narrowing of the arterial ...
The aorta (/ eɪ ˈ ɔːr t ə / ay-OR-tə; pl.: aortas or aortae) is the main and largest artery in the human body, originating from the left ventricle of the heart, branching upwards immediately after, and extending down to the abdomen, where it splits at the aortic bifurcation into two smaller arteries (the common iliac arteries).
Aortic unfolding is an abnormality visible on a chest X-ray, that shows widening of the mediastinum which may mimic the appearance of a thoracic aortic aneurysm. [ 1 ] With aging, the ascending portion of the thoracic aorta increases in length by approximately 12% per decade, whereas the diameter increases by just 3% per decade.
Fatty streak. A fatty streak is the first grossly visible (visible to the naked eye) lesion in the development of atherosclerosis. It appears as an irregular yellow-white discoloration on the luminal surface of an artery. It consists of aggregates of foam cells, which are lipoprotein -loaded macrophages, [ 1] located in the intima, the ...
Coronary artery disease ( CAD ), also called coronary heart disease ( CHD ), ischemic heart disease ( IHD ), [ 13] myocardial ischemia, [ 14] or simply heart disease, involves the reduction of blood flow to the cardiac muscle due to build-up of atherosclerotic plaque in the arteries of the heart. [ 5][ 6][ 15] It is the most common of the ...
Arteriosclerosis, literally meaning "hardening of the arteries", is an umbrella term for a vascular disorder characterized by abnormal thickening, hardening, and loss of elasticity [3] of the walls of arteries; [4] this process gradually restricts the blood flow to one's organs and tissues and can lead to severe health risks brought on by atherosclerosis, which is a specific form of ...