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An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamine or ethylamine, or ...
Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. [ 5][ 10][ 11] PCP works primarily as an NMDA receptor antagonist. [ 10] PCP is most commonly used in the United States. [ 12] While usage peaked in the US in the 1970s, [ 13] between 2005 and 2011 an increase in visits to ...
Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, [2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable ...
Hinsberg reaction. The Hinsberg reaction is a chemical test for the detection of primary, secondary and tertiary amines. The reaction was first described by Oscar Hinsberg in 1890. [ 1][ 2] In this test, the amine is shaken well with the Hinsberg reagent ( benzenesulfonyl chloride) in the presence of aqueous alkali (either KOH or NaOH).
By Manas Mishra and Puyaan Singh. (Reuters) -The European Union's drugs regulator has rejected Eisai and Biogen's Leqembi treatment for early Alzheimer's disease, saying the risk of serious brain ...
Carbylamine reaction. The carbylamine reaction (also known as the Hoffmann isocyanide synthesis) is the synthesis of an isocyanide by the reaction of a primary amine, chloroform, and base. The conversion involves the intermediacy of dichlorocarbene. Illustrative is the synthesis of tert -butyl isocyanide from tert -butylamine in the presence of ...
Dave Ramsey says 'very few people' who look like they have money actually do — claims vastly expensive cars, vacations on social media are rarely signs of real wealth.
Water quality data used by Paris Olympics organizers shows that bacteria levels in the Seine River were within acceptable levels on the days that athletes swam in the famed waterway, according to ...