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Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide -based reagents used as accelerators for vulcanization. The amine itself is an effective corrosion inhibitor. It has been used as a flushing aid in the printing ink industry. [ 5]
Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. [ 5][ 10][ 11] PCP works primarily as an NMDA receptor antagonist. [ 10] PCP is most commonly used in the United States. [ 12] While usage peaked in the US in the 1970s, [ 13] between 2005 and 2011 an increase in visits to ...
An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamine or ethylamine, or ...
Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, [2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable ...
Chemical synthesis ( chemical combination) is the artificial execution of chemical reactions to obtain one or several products. [ 1] This occurs by physical and chemical manipulations usually involving one or more reactions. In modern laboratory uses, the process is reproducible and reliable. A chemical synthesis involves one or more compounds ...
A Furukawa-modified Simmons-Smith generated cyclopropane intermediate is formed in the synthesis of γ-keto esters from β-keto esters. The Simmons-Smith reagent binds first to the carbonyl group and subsequently to the α-carbon of the pseudo-enol that the first reaction forms. This second reagent forms the cyclopropyl intermediate which ...
Fluorexetamine ( 3'-Fluoro-2-oxo-PCE, 3-FXE) is a recreational designer drug from the arylcyclohexylamine family, with dissociative effects. It has reportedly been sold over the internet since around 2017, though has remained relatively uncommon. [ 1]
Stereochemistry focuses on stereoisomers. Stereochemistry, a subdiscipline of chemistry, involves the study of the relative spatial arrangement of atoms that form the structure of molecules and their manipulation. [ 1] The study of stereochemistry focuses on the relationships between stereoisomers, which by definition have the same molecular ...