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Anticholinergic drugs are used to treat a variety of conditions: Dizziness (including vertigo and motion sickness-related symptoms) Extrapyramidal symptoms, a potential side-effect of antipsychotic medications; Gastrointestinal disorders (e.g., peptic ulcers, diarrhea, pyloro spasm, diverticulitis, ulcerative colitis, nausea, and vomiting)
Cholinergic blocking drugs are a group of drugs that block the action of acetylcholine (ACh), a neurotransmitter, in synapses of the cholinergic nervous system. [1] They block acetylcholine from binding to cholinergic receptors, namely the nicotinic and muscarinic receptors. These agents have broad effects due to their actions in nerves located ...
A muscarinic receptor antagonist ( MRA ), also called an antimuscarinic, is a type of anticholinergic agent that blocks the activity of the muscarinic acetylcholine receptor. The muscarinic receptor is a protein involved in the transmission of signals through certain parts of the nervous system, and muscarinic receptor antagonists work to ...
Oxybutynin, sold under the brand name Ditropan among others, is an anticholinergic medication primarily used to treat overactive bladder.It is widely considered a first-line therapy for overactive bladder due to its well-studied side effect profile, broad applicability, and continued efficacy over long periods of time.
Side Effects. Sedation, weight gain, metabolic changes, anticholinergic effects, extrapyramidal symptoms, tardive dyskinesia ... anticholinergic effects, extrapyramidal symptoms, tardive ...
Side effects of doxylamine include dizziness, drowsiness, and dry mouth, among others. [4] Doxylamine is a potent anticholinergic and has a side-effect profile common to such drugs, including blurred vision, dry mouth, constipation, muscle incoordination, urinary retention, mental confusion, and delirium. [18] [7]
Acetylcholinesterase inhibitors ( AChEIs) also often called cholinesterase inhibitors, [ 1] inhibit the enzyme acetylcholinesterase from breaking down the neurotransmitter acetylcholine into choline and acetate, [ 2] thereby increasing both the level and duration of action of acetylcholine in the central nervous system, autonomic ganglia and ...
Increased concentrations of nortriptyline may increase the risk for side effects, including anticholinergic and nervous system adverse effects, while decreased concentrations may reduce the drug's efficacy. [37] [38] [39] Individuals can be categorized into different types of CYP2D6 metabolizers depending on which genetic variations they carry ...