Search results
Results From The WOW.Com Content Network
Chemically, PCP is a member of the arylcyclohexylamine class, and pharmacologically, it is a dissociative anesthetic. [ 5][ 10][ 11] PCP works primarily as an NMDA receptor antagonist. [ 10] PCP is most commonly used in the United States. [ 12] While usage peaked in the US in the 1970s, [ 13] between 2005 and 2011 an increase in visits to ...
An arylcyclohexylamine is composed of a cyclohexylamine unit with an aryl moiety attachment. The aryl group is positioned geminal to the amine. In the simplest cases, the aryl moiety is typically a phenyl ring, sometimes with additional substitution. The amine is usually not primary; secondary amines such as methylamine or ethylamine, or ...
Eticyclidine (PCE, CI-400) is a dissociative anesthetic drug with hallucinogenic effects. It is similar in effects to phencyclidine but is slightly more potent. PCE was developed by Parke-Davis in the 1970s and evaluated for anesthetic potential under the code name CI-400, [2] but research into PCE was not continued after the development of ketamine, a similar drug with more favourable ...
Cyclohexylamine is used as an intermediate in synthesis of other organic compounds. It is the precursor to sulfenamide -based reagents used as accelerators for vulcanization. The amine itself is an effective corrosion inhibitor. It has been used as a flushing aid in the printing ink industry. [ 5]
In some literature articles, the terms "mechanism of action" and "mode of action" are used interchangeably, typically referring to the way in which the drug interacts and produces a medical effect. However, in actuality, a mode of action describes functional or anatomical changes, at the cellular level, resulting from the exposure of a living ...
A myriad of drug-cellular interactions have been documented in the scientific literature and these vary with respect to the properties of target cells, drug dose and drug intermediates produced. Since artefactual mechanisms of action can be observed, [ 26 ] the following mechanisms which occur at clinically relevant drug concentrations are the ...
Phentermine (phenyl-tertiary-butyl amine), sold under the brand name Ionamin among others, is a medication used together with diet and exercise to treat obesity. [3] It is taken by mouth for up to a few weeks at a time, after which the benefits subside. [3]
β-lactam antibiotics ( beta-lactam antibiotics) are antibiotics that contain a beta-lactam ring in their chemical structure. This includes penicillin derivatives ( penams ), cephalosporins and cephamycins ( cephems ), monobactams, carbapenems [ 1] and carbacephems. [ 2] Most β-lactam antibiotics work by inhibiting cell wall biosynthesis in ...