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The tables below contain a sample list of benzodiazepines and benzodiazepine analogs that are commonly prescribed, with their basic pharmacological characteristics, such as half-life and equivalent doses to other benzodiazepines, also listed, along with their trade names and primary uses. The elimination half-life is how long it takes for half ...
Benzodiazepines ( BZD, BDZ, BZs ), colloquially called " benzos ", are a class of depressant drugs whose core chemical structure is the fusion of a benzene ring and a diazepine ring. They are prescribed to treat conditions such as anxiety disorders, insomnia, and seizures. The first benzodiazepine, chlordiazepoxide (Librium), was discovered ...
The benzodiazepines are a class of drugs with hypnotic, anxiolytic, anticonvulsive, amnestic and muscle relaxant properties. Benzodiazepines act as a central nervous system depressant. The relative strength of each of these properties in any given benzodiazepine varies greatly and influences the indications for which it is prescribed.
Benzodiazepines may also cause or worsen depression. [19] Infusions or repeated intravenous injections of diazepam when managing seizures, for example, may lead to drug toxicity, including respiratory depression, sedation and hypotension. Drug tolerance may also develop to infusions of diazepam if it is given for longer than 24 hours. [19]
Lorazepam, sold under the brand name Ativan among others, is a benzodiazepine medication. [ 7] It is used to treat anxiety (including anxiety disorders ), trouble sleeping, severe agitation, active seizures including status epilepticus, alcohol withdrawal, and chemotherapy-induced nausea and vomiting. [ 7]
Aricept ( donepezil) – used to slow the progression of Alzheimer's disease. Ativan ( lorazepam) – a benzodiazepine, used to treat anxiety. Asendin ( amoxapine) – an dibenzoxazepine antidepressant. Azstarys ( Serdexmethylphenidate / Dexmethylphenidate) - a long-acting CNS stimulant used to treat ADHD.
The choice of the benzodiazepine will depend on the corresponding profiles. [9] Benzodiazepines are used for emergent or short-term management. They are not recommended as the first-line anti-anxiety drugs, but they can be used in combination with SSRIs/SNRIs during the initial treatment stage. [4]
Symptoms. Effects of long-term benzodiazepine use may include disinhibition, impaired concentration and memory, depression, [ 19][ 20] as well as sexual dysfunction. [ 6][ 21] The long-term effects of benzodiazepines may differ from the adverse effects seen after acute administration of benzodiazepines. [ 22]