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Gabapentin, sold under the brand name Neurontin among others, is an anticonvulsant medication primarily used to treat partial seizures and neuropathic pain. [ 7 ] [ 10 ] It is a commonly used medication for the treatment of neuropathic pain caused by diabetic neuropathy , postherpetic neuralgia , and central pain . [ 11 ]
In April 2019, [55] the United Kingdom scheduled gabapentin and pregabalin as Class C drugs under the Misuse of Drugs Act 1971, and as Schedule 3 under the Misuse of Drugs Regulations 2001. [56] However, it is not a controlled substance in Canada, or Australia, and the other gabapentinoids, including phenibut, are not controlled substances ...
List of Schedule III controlled substances (U.S.) This is the list of Schedule III controlled substances in the United States as defined by the Controlled Substances Act at 21 U.S.C. § 812 (c) and 21 CFR 1308.13. The following findings are required for substances to be placed in this schedule: [ 1]
Gabapentin enacarbil ( Horizant ( ER) ( U.S. ), Regnite (in Japan )) is an anticonvulsant and analgesic drug of the gabapentinoid class, and a prodrug to gabapentin. [ 1] It was designed for increased oral bioavailability over gabapentin, [ 2][ 3] and human trials showed it to produce extended release of gabapentin with almost twice the overall ...
Clonazepam, sold under the brand names Klonopin and Rivotril, is a medication used to prevent and treat anxiety disorders, seizures, bipolar mania, agitation associated with psychosis, obsessive–compulsive disorder, and akathisia. [ 11] It is a long-acting [ 12] tranquilizer of the benzodiazepine class. [ 11]
Baclofen, sold under the brand name Lioresal among others, is a medication used to treat muscle spasticity such as from a spinal cord injury or multiple sclerosis. [ 8][ 9] It may also be used for hiccups and muscle spasms near the end of life, [ 9] and off-label to treat alcohol use disorder [ 10][ 11] or opioid withdrawal symptoms. [ 12]
Gabapentin was designed by researchers at Parke-Davis to be an analogue of the neurotransmitter GABA that could more easily cross the blood–brain barrier and was first described in 1975 by Satzinger and Hartenstein. [22] [23] Gabapentin was first approved for epilepsy, mainly as an add-on treatment for partial seizures.
Nortriptyline, sold under the brand name Aventyl, among others, is a tricyclic antidepressant. This medicine is also sometimes used for neuropathic pain, attention deficit hyperactivity disorder (ADHD), smoking cessation and anxiety. [ 5][ 6] As with many antidepressants, its use for young people with depression and other psychiatric disorders ...