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Hydroxychloroquine, sold under the brand name Plaquenil among others, is a medication used to prevent and treat malaria in areas where malaria remains sensitive to chloroquine. Other uses include treatment of rheumatoid arthritis , lupus , and porphyria cutanea tarda .
Hydroxychloroquine is more commonly available than chloroquine in the United States. [13] Hydroxychloroquine is used as a prophylactic in India. [24] [25] Hydroxychloroquine and chloroquine have numerous, potentially serious, side effects, such as retinopathy, hypoglycemia, or life-threatening arrhythmia and cardiomyopathy. [26]
A World Health Organization infographic that states that hydroxychloroquine does not prevent illness or death from COVID-19. Chloroquine and hydroxychloroquine are anti-malarial medications also used against some auto-immune diseases. [64] Chloroquine, along with hydroxychloroquine, was an early experimental treatment for COVID-19. [65]
Biological half-life. Time course of drug plasma concentrations over 96 hours following oral administrations every 24 hours (τ). Absorption half-life 1 h, elimination half-life 12 h. Biological half-life ( elimination half-life, pharmacological half-life) is the time taken for concentration of a biological substance (such as a medication) to ...
Antimalarial medication. Antimalarial medications or simply antimalarials are a type of antiparasitic chemical agent, often naturally derived, that can be used to treat or to prevent malaria, in the latter case, most often aiming at two susceptible target groups, young children and pregnant women. [ 1] As of 2018, modern treatments, including ...
Half-life (symbol t½) is the time required for a quantity (of substance) to reduce to half of its initial value. The term is commonly used in nuclear physics to describe how quickly unstable atoms undergo radioactive decay or how long stable atoms survive. The term is also used more generally to characterize any type of exponential (or, rarely ...
Radioactive isotope table "lists ALL radioactive nuclei with a half-life greater than 1000 years", incorporated in the list above. The NUBASE2020 evaluation of nuclear physics properties F.G. Kondev et al. 2021 Chinese Phys. C 45 030001. The PDF of this article lists the half-lives of all known radioactives nuclides.
Mefloquine is a chiral molecule with two asymmetric carbon centres, which means it has four different stereoisomers. The drug is currently manufactured and sold as a racemate of the ( R, S )- and ( S, R )-enantiomers by Hoffmann-La Roche, a Swiss pharmaceutical company. Essentially, it is two drugs in one.