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2. Biden administration says Medicare negotiated price discounts ...

   www.aol.com/news/biden-administration-says...

   The list price of Merck's diabetes drug Januvia will be slashed to $113 for a 30-day supply from $527 as of 2023. Eliquis, a blood thinner from Bristol Myers Squibb and Pfizer, will cost $231 for ...

3. What are the drugs affected by Medicare deal to lower costs?

   www.aol.com/news/know-medicare-negotiation...

   Here are the 10 drugs and their negotiated prices for a one-month supply: Januvia treats diabetes. The negotiated price is $113 (£103), down 79%. Fiasp, Fiasp FlexTouch, Fiasp PenFill, NovoLog ...

4. Biden admin announces results of historic Medicare drug price ...

   www.aol.com/medicare-enrollees-save-billions...

   The number rises to 20 drugs a year for 2029 and beyond. In the first two years of negotiations, only Part D drugs that are purchased at pharmacies will be included.

5. First-Time Negotiations Have Lowered Prices On 10 Expensive ...

   www.aol.com/biden-announce-drug-price-agreements...

   For Eliquis, a Bristol Myers Squibb drug that nearly 4 million Medicare beneficiaries take to treat blood clots, the current net price for a 30-day supply is about $309, according to calculations ...

6. Apixaban - Wikipedia

   en.wikipedia.org/wiki/Apixaban

   Apixaban. Apixaban, sold under the brand name Eliquis, is an anticoagulant medication used to treat and prevent blood clots and to prevent stroke in people with nonvalvular atrial fibrillation through directly inhibiting factor Xa. [ 6][ 7][ 8] Specifically, it is used to prevent blood clots following hip or knee replacement and in those with a ...

7. These are the drugs that are getting cheaper under new ... - AOL

   www.aol.com/drugs-getting-cheaper-under-medicare...

   A 30 day supply of each currently costs around $520, but in 2026 — that price will be cut in more than half as each will cost closer to $200. Even more savings will come with the three diabetes ...

8. Direct factor Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Direct_factor_Xa_inhibitors

   Medical use. Direct factor Xa inhibitors include rivaroxaban, apixaban and edoxaban, and are types of direct oral anticoagulant (DOAC), which are blood thinning drugs, one of the classes of antithrombotic drugs. [ 4][ 5][ 6] They are commonly prescribed to treat and prevent blood clots in veins, prevent stroke and embolism in people with non ...

9. Discovery and development of direct Xa inhibitors - Wikipedia

   en.wikipedia.org/wiki/Discovery_and_development...

   The pyrazole N-2 nitrogen atom of apixaban interacts with Gln-192 and the carbonyl oxygen interacts with Gly-216. The phenyl lactam group of apixaban is positioned between Tyr-99 and Phe-174 and due to its orientation, it is able to interact with Trp-215 of the S4 pocket.