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  2. Target Corporation - Wikipedia

    en.wikipedia.org/wiki/Target_Corporation

    The company is one of the largest American-owned private employers in the United States. The corporation was founded in Minneapolis by businessman George Dayton in 1902, and developed through the years via expansion and acquisitions. Target, the company's first discount store and eventual namesake, was opened in 1962.

  3. List of Walmart brands - Wikipedia

    en.wikipedia.org/wiki/List_of_Walmart_brands

    Equate is an example of the strength of Walmart's private label store brand. In a 2006 study, The Hartman Group marketing research firm issued a report which found that "Five of the top 10 "likely to purchase" private label brands are managed by Walmart including: Great Value, Equate, Sam's Choice, Walmart, and Member's Mark (Sam's Club), per ...

  4. Proteolysis targeting chimera - Wikipedia

    en.wikipedia.org/wiki/Proteolysis_targeting_chimera

    A proteolysis targeting chimera ( PROTAC) [ 2] is a molecule that can remove specific unwanted proteins. Rather than acting as a conventional enzyme inhibitor, a PROTAC works by inducing selective intracellular proteolysis. A heterobifunctional molecule with two active domains and a linker, PROTACs consist of two covalently linked protein ...

  5. Is Madrigal Pharmaceuticals Stock a Buy? - AOL

    www.aol.com/madrigal-pharmaceuticals-stock-buy...

    Some analysts predict peak sales above $4 billion or even $5 billion. There is competition on the way Although Madrigal was first-to-market in NASH, many prominent drugmakers are now hot on its heels.

  6. Imatinib - Wikipedia

    en.wikipedia.org/wiki/Imatinib

    The drug is approved in multiple contexts of Philadelphia chromosome-positive CML, including after stem cell transplant, in blast crisis, and newly diagnosed. [ 11 ] Due in part to the development of imatinib and related drugs, the five-year survival rate for people with chronic myeloid leukemia increased from 31% in 1993, to 59% in 2009, [ 12 ...

  7. Eculizumab - Wikipedia

    en.wikipedia.org/wiki/Eculizumab

    Eculizumab, sold under the brand name Soliris among others, is a recombinant humanized monoclonal antibody used to treat paroxysmal nocturnal hemoglobinuria, atypical hemolytic uremic syndrome, generalized myasthenia gravis, and neuromyelitis optica. [ 8][ 9] In people with paroxysmal nocturnal hemoglobinuria, it reduces both the destruction of ...

  8. 5 Best Back-to-School Items To Buy at Target With a $50 Budget

    www.aol.com/finance/5-best-back-school-items...

    Target sells Crayola products, which are known for their quality and affordability. A 24-pack of Crayola crayons costs $1.49, but they’re currently on sale for just $0.50. A 10-pack of Crayola ...

  9. List of largest companies in the United States by revenue

    en.wikipedia.org/wiki/List_of_largest_companies...

    The Fortune 500 list of companies includes only publicly traded companies, also including tax inversion companies. There are also corporations having foundation in the United States, such as corporate headquarters, operational headquarters and independent subsidiaries.