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[103] [107] [109] [110] [111] Warner-Lambert management was concerned that atorvastatin was a me-too version of rival Merck & Co.'s orphan drug lovastatin (brand name Mevacor). Mevacor, which was first marketed in 1987, was the industry's first statin and Merck's synthetic version – simvastatin – was in the advanced stages of development ...
The class is on the World Health Organization's List of Essential Medicines with simvastatin being the listed medicine. [10] In 2005, sales were estimated at US$18.7 billion in the United States. [11] The best-selling statin is atorvastatin, also known as Lipitor, which in 2003 became the best-selling pharmaceutical in history. [12]
D08488. CompTox Dashboard (EPA) DTXSID101027010. (verify) Amlodipine/atorvastatin, sold under the brand name Caduet among others, is a fixed-dose combination medication for the treatment of high cholesterol and high blood pressure. It contains a statin and a calcium channel blocker. [1] [2]
Fluvastatin is a member of the statin drug class, used to treat hypercholesterolemia and to prevent cardiovascular disease . It was patented in 1982 and approved for medical use in 1994. [ 4] It is on the World Health Organization's List of Essential Medicines. [ 5]
Aponal, Quitaxon, Sinequan ( doxepin) – a tricyclic antidepressant used to treat nerve pain, insomnia; similar to imipramine. Anquil ( benperidol) – an antipsychotic primarily used to control antisocial hypersexual behaviour. Aricept ( donepezil) – used to slow the progression of Alzheimer's disease. Ativan ( lorazepam) – a ...
Lovastatin, sold under the brand name Mevacor among others, is a statin medication, to treat high blood cholesterol and reduce the risk of cardiovascular disease. [2] Its use is recommended together with lifestyle changes. [2]
Rosuvastatin. Rosuvastatin, sold under the brand name Crestor among others, is a statin medication, used to prevent cardiovascular disease in those at high risk and treat abnormal lipids. [ 6] It is recommended to be used together with dietary changes, exercise, and weight loss. [ 6] It is taken orally (by mouth).
Simvastatin. Simvastatin, sold under the brand name Zocor among others, is a statin, a type of lipid-lowering medication. [ 4] It is used along with exercise, diet, and weight loss to decrease elevated lipid levels. [ 4] It is also used to decrease the risk of heart problems in those at high risk. [ 4] It is taken by mouth.
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