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  2. Smallpox vaccine - Wikipedia

    en.wikipedia.org/wiki/Smallpox_vaccine

    The smallpox vaccine is the first vaccine to have been developed against a contagious disease. In 1796, British physician Edward Jenner demonstrated that an infection with the relatively mild cowpox virus conferred immunity against the deadly smallpox virus. Cowpox served as a natural vaccine until the modern smallpox vaccine emerged in the ...

  3. History of smallpox - Wikipedia

    en.wikipedia.org/wiki/History_of_smallpox

    The history of smallpox extends into pre-history. [ 1] Genetic evidence suggests that the smallpox virus emerged 3,000 to 4,000 years ago. [ 2] Prior to that, similar ancestral viruses circulated, but possibly only in other mammals, and possibly with different symptoms. Only a few written reports dating from about 500 AD to 1000 AD are ...

  4. Smallpox - Wikipedia

    en.wikipedia.org/wiki/Smallpox

    Smallpox was an infectious disease caused by variola virus (often called smallpox virus), which belongs to the genus Orthopoxvirus. [7] [11] The last naturally occurring case was diagnosed in October 1977, and the World Health Organization (WHO) certified the global eradication of the disease in 1980, [10] making smallpox the only human disease to have been eradicated to date.

  5. Tuberculosis - Wikipedia

    en.wikipedia.org/wiki/Tuberculosis

    Tuberculosis ( TB ), also known colloquially as the " white death ", or historically as consumption, [7] is an infectious disease usually caused by Mycobacterium tuberculosis (MTB) bacteria. [1] Tuberculosis generally affects the lungs, but it can also affect other parts of the body. [1] Most infections show no symptoms, in which case it is ...

  6. Leprosy - Wikipedia

    en.wikipedia.org/wiki/Leprosy

    People living in the same home as a person with leprosy are suggested to take a BCG booster which may improve their immunity by 56%. [80] [81] Development of a more effective vaccine is ongoing. [14] [82] [83] [84] A novel vaccine called LepVax entered clinical trials in 2017 with the first encouraging results reported on 24 participants ...

  7. Rinderpest - Wikipedia

    en.wikipedia.org/wiki/Rinderpest

    Rinderpest is believed to have originated in Asia, and to have spread by transport of cattle. [ 5][ 6][ 7] The term Rinderpest ( German: [ˈʁɪndɐˌpɛst] ⓘ) is a German word meaning "cattle plague". [ 2][ 7] The rinderpest virus (RPV) is closely related to the measles and canine distemper viruses. [ 8] The measles virus may have emerged ...

  8. Diphtheria - Wikipedia

    en.wikipedia.org/wiki/Diphtheria

    The 1 million cases in Europe resulted in 50,000 deaths. [citation needed] During 1948 in Kyoto, 68 of 606 children died after diphtheria immunization due to improper manufacture of aluminum phosphate toxoid. [62] In 1974, the World Health Organization included DPT vaccine in their Expanded Programme on Immunization for developing countries ...

  9. Black Death - Wikipedia

    en.wikipedia.org/wiki/Black_Death

    25,000,000 – 50,000,000 (estimated) The Black Death was a bubonic plague pandemic occurring in Europe from 1346 to 1353. It was one of the most fatal pandemics in human history; as many as 50 million people [ 2] perished, perhaps 50% of Europe's 14th century population. [ 3] The disease is caused by the bacterium Yersinia pestis and spread by ...