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Chronic granulomatous disease (CGD), also known as Bridges–Good syndrome, chronic granulomatous disorder, and Quie syndrome, is a diverse group of hereditary diseases in which certain cells of the immune system have difficulty forming the reactive oxygen compounds (most importantly the superoxide radical due to defective phagocyte NADPH oxidase) used to kill certain ingested pathogens.
Founded. 10 April 1876 (1876-04-10) Headquarters. Lisbon, Portugal. Key people. Paulo Macedo (CEO) Website. www .cgd .pt. Caixa Geral de Depósitos (CGD) ( Portuguese pronunciation: [ˈkajʃɐ ʒɨˈɾal dɨ ðɨˈpɔzituʃ]) is a Portuguese state-owned banking corporation, and the largest bank in Portugal, established in Lisbon in 1876.
The Center for Global Development in Europe was established in October 2011 with the aim of engaging with and learning from policymakers, academics, and researchers in Europe, and bringing the CGD blend of evidence-led, high-quality research and engagement to European policymaking and engagement about development.
Prolonged grief disorder ( PGD ), also known as complicated grief ( CG ), [1] traumatic grief ( TG) [2] and persistent complex bereavement disorder ( PCBD) in the DSM-5, [3] is a mental disorder consisting of a distinct set of symptoms following the death of a family member or close friend (i.e. bereavement ). People with PGD are preoccupied by ...
Specialty. Neurology. A congenital disorder of glycosylation (previously called carbohydrate-deficient glycoprotein syndrome) is one of several rare inborn errors of metabolism in which glycosylation of a variety of tissue proteins and/or lipids is deficient or defective. Congenital disorders of glycosylation are sometimes known as CDG syndromes.
Immunodeficiency, also known as immunocompromisation, is a state in which the immune system 's ability to fight infectious diseases and cancer is compromised or entirely absent. Most cases are acquired ("secondary") due to extrinsic factors that affect the patient's immune system. Examples of these extrinsic factors include HIV infection and ...
NOX2. NADPH oxidase 2 ( Nox2 ), also known as cytochrome b (558) subunit beta or Cytochrome b-245 heavy chain, is a protein that in humans is encoded by the NOX2 gene (also called CYBB gene). [5] The protein is a superoxide generating enzyme which forms reactive oxygen species (ROS).
The Commitment to Development Index ( CDI ), published annually by the Center for Global Development, ranks the world's richest countries on their dedication to policies that benefit the five billion people living in poorer nations. Rich and poor countries are linked in many ways; thus the Index looks beyond standard comparisons of foreign aid ...