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Enzyme unit. The enzyme unit, or international unit for enzyme (symbol U, sometimes also IU) is a unit of enzyme 's catalytic activity. [1] 1 U (μmol/min) is defined as the amount of the enzyme that catalyzes the conversion of one micro mole of substrate per minute under the specified conditions of the assay method. [2]
Gamma-glutamyltransferase (also γ-glutamyltransferase, GGT, gamma-GT, gamma-glutamyl transpeptidase; [1] EC 2.3.2.2) is a transferase (a type of enzyme) that catalyzes the transfer of gamma- glutamyl functional groups from molecules such as glutathione to an acceptor that may be an amino acid, a peptide or water (forming glutamate ).
The Enzyme Commission number ( EC number) is a numerical classification scheme for enzymes, based on the chemical reactions they catalyze. [1] As a system of enzyme nomenclature, every EC number is associated with a recommended name for the corresponding enzyme-catalyzed reaction. EC numbers do not specify enzymes but enzyme-catalyzed reactions.
Glucose-6-phosphate dehydrogenase ( G6PD or G6PDH) ( EC 1.1.1.49) is a cytosolic enzyme that catalyzes the chemical reaction. D -glucose 6-phosphate + NADP + + H2O ⇌ 6-phospho- D -glucono-1,5-lactone + NADPH + H +. This enzyme participates in the pentose phosphate pathway (see image), a metabolic pathway that supplies reducing energy to cells ...
View/Edit Mouse. Activation-induced cytidine deaminase, also known as AICDA, AID and single-stranded DNA cytosine deaminase, is a 24 kDa enzyme which in humans is encoded by the AICDA gene. [ 5] It creates mutations in DNA [ 6][ 7] by deamination of cytosine base, which turns it into uracil (which is recognized as a thymine ).
Biochemistry. Enzymes ( / ˈɛnzaɪmz /) are proteins that act as biological catalysts by accelerating chemical reactions. The molecules upon which enzymes may act are called substrates, and the enzyme converts the substrates into different molecules known as products.
Turnover number. In chemistry, the term " turnover number " has two distinct meanings. In enzymology, the turnover number ( kcat) is defined as the limiting number of chemical conversions of substrate molecules per second that a single active site will execute for a given enzyme concentration [ET] for enzymes with two or more active sites. [1 ...
Glucuronosyltransferases are responsible for the process of glucuronidation, a major part of phase II metabolism. Arguably the most important of the Phase II (conjugative) enzymes, UGTs have been the subject of increasing scientific inquiry since the mid-to-late 1990s. The reaction catalyzed by the UGT enzyme involves the addition of a ...